| Date | Location | Result | |
| 03/08/21 | Sioux Falls, S.D. (Sanford Pentagon) | North Dakota St. 79, South Dakota 75 | Box score |
| 03/06/21 | Sioux Falls, S.D. (Sanford Pentagon) | South Dakota 86, Western Ill. 69 | Box score |
| 02/28/21 | Vermillion, S.D. (Sanford Coyote SC) | North Dakota St. 89, South Dakota 77 | Box score |
| 02/27/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 80, North Dakota St. 71 | Box score |
| 02/20/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 86, Oral Roberts 84 | Box score |
| 02/14/21 | Grand Forks, N.D. (Engelstad Center) | North Dakota 85, South Dakota 81 | Box score |
| 02/13/21 | Grand Forks, N.D. (Engelstad Center) | North Dakota 85, South Dakota 76 | Box score |
| 02/06/21 | Brookings, S.D. (Frost Arena) | South Dakota St. 89, South Dakota 78 | Box score |
| 02/05/21 | Brookings, S.D. (Frost Arena) | South Dakota 64, South Dakota St. 56 | Box score |
| 01/30/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 97, Omaha 93 | Box score |
| 01/29/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 91, Omaha 59 | Box score |
| 01/23/21 | Macomb, Ill. (Western Hall) | South Dakota 84, Western Ill. 74 | Box score |
| 01/22/21 | Macomb, Ill. (Western Hall) | South Dakota 65, Western Ill. 60 | Box score |
| 01/09/21 | Kansas City, Mo. (Swinney Center) | South Dakota 68, Kansas City 62 | Box score |
| 01/08/21 | Kansas City, Mo. (Swinney Center) | South Dakota 66, Kansas City 64 | Box score |
| 01/03/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 79, Denver 57 | Box score |
| 01/02/21 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 93, Denver 54 | Box score |
| 12/20/20 | Vermillion, S.D. (Sanford Coyote SC) | South Dakota 84, Mt. Marty 44 | Box score |
| 12/18/20 | Vermillion, S.D. (Sanford Coyote SC) | Drake 75, South Dakota 57 | Box score |
| 12/12/20 | Sioux Falls, S.D. (Sanford Pentagon) | South Dakota 91, South Dakota St. 78 | Box score |
| 12/11/20 | Sioux Falls, S.D. (Sanford Pentagon) | North Dakota St. 74, South Dakota 67 | Box score |
| 12/10/20 | Sioux Falls, S.D. (Sanford Pentagon) | North Dakota 75, South Dakota 71 | Box score |
| 12/01/20 | Lincoln, Neb. (Pinnacle Bank Arena) | Nebraska 76, South Dakota 69 | Box score |
| 11/27/20 | Manhattan, Kan. (Bramlage Coliseum) | Drake 69, South Dakota 53 | Box score |
| 11/25/20 | Manhattan, Kan. (Bramlage Coliseum) | Colorado 84, South Dakota 61 | Box score |